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Incidence of Silent Lacunar Lesion in Normal Adults and Its Relation to Cerebral Blood Flow and Risk Factors
Stroke 22:1379-1383, Kobayashi,S.,et al, 1991
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Article Abstract
Thirty-two subjects(13%)had possible silent lacunar lesions(66%of these were recognized by both T1-and T2-weighted image).The regional cerebral blood flow measured by the xenon-133 inhalation method was significantly lower in subjects with silent lacunes than in those without(p<0.02). Cerebral blood flow was mildly but significantly decreased in those with silent lacunes(p<0.05).Periventricular hyperintensity was closely related to silent lacune(p<0.01).However,there was no significant difference in cerebral blood flow between subjects with and without apparent periventricular hyperintensity.Silent lacunar lesion was closely related to decrease of cerebral circulation and may be an important risk factor for symptomatic cerebrovascular disease.
 
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cerebral blood flow
cerebrovascular accident,silent
cerebrovascular disease,risk factors in
lacunar infarction
lacunar infarction,asymptomatic
MRI
MRI,abnormal

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